In this episode of Big Bang Theory, Amy uses operant conditioning on Sheldon and his need to have closure for everything. Operant conditioning is methods of different attempts to alter ones behavior with either negative or positive reinforcement. Amy does this with Sheldon, going through multiple activities that have a start and finish to them. However, she never finishes them so Sheldon can learn to live through his life without closure. In result, Amy tries to fix his need of having constant closure over everything.